Infectious diseases are a major cause of death and disability throughout the world. Research in the Linnes Lab focuses on using state of the art microfluidic and paperfluidic technologies to prevent, detect, and better understand the pathogenesis of these infectious diseases. In particular, these include developing point of care diagnostics for rapid disease detection, and determining the efficacy of therapeutic interventions via miniaturized bioassays for low resource settings. Working with our clinical collaborators in the field, we leverage and skills in microfluidic cell capture and rapid investigation of disease identity to efficiently diagnose a variety of environmental, bacterial, and viral pathogens at the point of care. Applications of this work range from global health to biodefense to personalized medicine.